J P Sommadossi

Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

Raymond F. Schinazi, A. McMillan, Deborah Cannon et al. · Antimicrobial Agents and Chemotherapy · 1992 · 291 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus

C. K. CHU, Tianwei Ma, Kirupa Shanmuganathan et al. · Antimicrobial Agents and Chemotherapy · 1995 · 229 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Toxicity of 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro

J P Sommadossi, R Carlisle · Antimicrobial Agents and Chemotherapy · 1987 · 188 citations · Full text

Pharmacy, Hematology, Toxicology +11

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

Raymond F. Schinazi, J P Sommadossi, Vanessa Saalmann et al. · Antimicrobial Agents and Chemotherapy · 1990 · 173 citations · Full text

Life Sciences, Immunology, Molecular Biology +8

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.

William Lewis, Eric S. Levine, B. Griniuvienė et al. · Proceedings of the National Academy of Sciences · 1996 · 164 citations

Life Sciences, Biochemistry, Genetics +17