Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis

Thomas Oligino, Steven C. Ghivizzani, Darren Wolfe, +6

Gene Therapy

InflammationRheumatologyRheumatoid DisorderAutoimmune DiseaseMedicine +10

Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase.

Shusuke Moriuchi, Thomas Oligino, D Krisky, +4

PubMed

Vector-directed CoexpressionTnf-alpha VectorCancer-associated VirusNeurovirologyImmunology +12

HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathy

Munmun Chattopadhyay, D Krisky, Darren Wolfe, +3

Gene Therapy

NeuroregenerationDiabetesDiabetic NeuropathyVascular BiologyNeurology +3

Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model

Jesús Gómez-Navarro, J. L. Contreras, Waleed Arafat, +8

Gene Therapy

Regenerative MedicineTissue EngineeringCell TherapyAngiogenesisEngineering +9

HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma

Shusuke Moriuchi, D Krisky, Peggy Marconi, +5

Gene Therapy

Cancer-associated VirusHsv Vector CytotoxicityImmunologyPathologyAdult T-cell Leukemia-lymphoma +6

Herpes simplex virus vector-mediated delivery of glial cell line-derived neurotrophic factor rescues erectile dysfunction following cavernous nerve injury

Ryuichi Kato, Darren Wolfe, Christian H. Coyle, +9

Gene Therapy

NeuroregenerationCavernous Nerve InjuryNeurovirologyMedicineNeurology +5

Replication-defective herpes simplex virus vectors for neurotrophic factor gene transfer in vitro and in vivo

Peggy Marconi, Michele Simonato, Silvia Zucchini, +5

Gene Therapy

Viral ReplicationMolecular VirologyNatural SciencesPathogenesisDna Replication +7

Herpes simplex virus vectors for gene transfer to the nervous system.

William F. Goins, D Krisky, Peggy Marconi, +5

PubMed

Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates

Darren Wolfe, Ajay Niranjan, Anita M. Trichel, +9

Gene Therapy

VaccinationNeurovirologyIntracranial DeliveryVirus TransmissionVirology +6

Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain

Yan Wang, Michal O. Nowicki, X Wang, +10

Gene Therapy

Pain ResearchAntinociceptive Gene TherapiesPain SyndromeHealth SciencesMedicine +11