Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier.

E A Neuwelt, Peggy A. Barnett, Darell D. Bigner, +1

Proceedings of the National Academy of Sciences

PharmacotherapyGlucocorticoidGliomaCerebral Vascular RegulationNeuro-oncology +17

Laboratory assessment of the status of Her-2/neu protein and oncogene in breast cancer specimens: comparison of immunohistochemistry assay with fluorescence in situ hybridisation assays

S Wang, M. Hossein Saboorian, E. P. Frenkel, +3

Journal of Clinical Pathology

Therapeutic Efficacy of Multiagent Chemotherapy with Drug Delivery Enhancement by Blood-Brain Barrier Modification in Glioblastoma

Edward A. Neuwelt, John Howieson, E. P. Frenkel, +4

Neurosurgery

Osmotic blood-brain barrier disruption. Computerized tomographic monitoring of chemotherapeutic agent delivery.

Edward A. Neuwelt, Kenneth R. Maravilla, E. P. Frenkel, +3

Journal of Clinical Investigation

PharmacotherapyBiomedical EngineeringCerebral Vascular RegulationBiomedical TechnologyIntracarotid Infusion +20

Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoprotein.

Sanjay Awasthi, Sharad S. Singhal, Sanjay Srivastava, +7

Journal of Clinical Investigation

Mechanism DistinctLipid PeroxidationCellular PharmacologyDnp-sg AtpaseChemical Biology +19

Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.

Demetrius M. Kokkinakis, Richard M. Hoffman, E. P. Frenkel, +4

PubMed

PathologyPharmacotherapyExperimental PharmacologyGliomaTumor Biology +15

A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging.

David I. Rosenthal, Pamela Nurenberg, Carlos Becerra, +8

PubMed

Imaging AgentPathologySelective BiolocalizationGliomaTumor Biology +17

Delivery of hexosaminidase A to the cerebrum after osmotic modification of the blood--brain barrier.

Edward A. Neuwelt, J. A. Barranger, Roscoe O. Brady, +5

Proceedings of the National Academy of Sciences

PharmacotherapyBiomedical EngineeringExperimental PharmacologyRat ModelNeurobiology Of Disease +17

DNA methylation-associated inactivation of TGFβ-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers

Makoto Suzuki, Hisayuki Shigematsu, David S. Shames, +8

British Journal of Cancer

Heterogeneity of the molecular lesions in inherited phosphofructokinase deficiency.

Shobhana Vora, Mercy M. Davidson, Carol Seaman, +5

Journal of Clinical Investigation

Electrolyte DisorderMetabolic DisorderIsolated HemolysisGeneticsPathology +16