CoCl₂, a Chemical Inducer of Hypoxia‐Inducible Factor‐1, and Hypoxia Reduce Apoptotic Cell Death in Hepatoma Cell Line HepG2

Jean‐Pascal Piret, Denis Mottet, Martine Raes, +1

Annals of the New York Academy of Sciences

Major Transcription FactorApoptosisImmunologyCell DeathCell Death Mechanisms +15

Hypoxia-inducible Factor-1-dependent Overexpression of Myeloid Cell Factor-1 Protects Hypoxic Cells against tert-Butyl Hydroperoxide-induced Apoptosis

Jean‐Pascal Piret, Emmanuel Minet, Jean-Philippe Cosse, +4

Journal of Biological Chemistry

Copper(ii) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response

Jean‐Pascal Piret, Diane Jacques, Jean‐Nicolas Audinot, +8

Nanoscale

NanotherapeuticsEngineeringMetal NanoparticlesLipid PeroxidationImmunology +24

c-JUN Gene Induction and AP-1 Activity Is Regulated by a JNK-Dependent Pathway in Hypoxic HepG2 Cells

Emmanuel Minet, Gaëtan Michel, Denis Mottet, +4

Experimental Cell Research

Reductive StressSignal TransductionCell RegulationRedox RegulatorMedicine +8

Hypoxia and CoCl2 protect HepG2 cells against serum deprivation- and t-BHP-induced apoptosis: a possible anti-apoptotic role for HIF-1

Jean‐Pascal Piret, Christophe Lecocq, Sébastien Toffoli, +3

Experimental Cell Research

InflammationT-bhp-induced ApoptosisMedicineHepg2 CellsApoptosis +10

Mitochondria permeability transition-dependent tert-butyl hydroperoxide-induced apoptosis in hepatoma HepG2 cells

Jean‐Pascal Piret, Thierry Arnould, B. B. Fuks, +3

Biochemical Pharmacology

Mitochondrial FunctionBiochemistryHepatoma Hepg2 CellsLiver PhysiologyLipid Peroxidation +5

Casein kinase 2 inhibition decreases hypoxia-inducible factor-1 activity under hypoxia through elevated p53 protein level

Antoine Hubert, Sébastien Paris, Jean‐Pascal Piret, +3

Journal of Cell Science

Cell DeathRedox BiologyOxidative StressInflammationTranscriptional Regulation +15

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

Jean‐Pascal Piret, Sébastien Vankoningsloo, Jorge Mejia, +8

Nanotoxicology

NanotherapeuticsEngineeringSimilar Hydrodynamic DiameterPathologyNanotoxicology +15

Hypoxia protects HepG2 cells against etoposide-induced apoptosis VIA a HIF-1-independent pathway

Jean‐Pascal Piret, Jean-Philippe Cosse, Noëlle Ninane, +2

Experimental Cell Research

InflammationReductive StressRedox RegulatorLiver PhysiologyApoptosis +12

Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis

Sébastien Vankoningsloo, Jean‐Pascal Piret, Christelle Saout, +6

Nanotoxicology

Tissue EngineeringEngineeringNanotoxicologyBiomedical EngineeringDermatology +16