Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial

Clara K Chow, Emily Atkins, Graham S. Hillis, +30

The Lancet

HypertensionAntihypertensive TherapyBlood Pressure MedicinesBlood Pressure ControlPharmacotherapy +5

Percutaneous Closure of Postinfarction Ventricular Septal Defect

Patrick A. Calvert, James Cockburn, D. Wynne, +18

Circulation

Coexistence of functioning beta 1- and beta 2-adrenoceptors in single myocytes from human ventricle.

Federica del Monte, Alberto J. Kaumann, PA Poole-Wilson, +3

Circulation

Clenbuterol Induces Hypertrophy of the Latissimus Dorsi Muscle and Heart in the Rat With Molecular and Phenotypic Changes

Mario Petrou, D. Wynne, Kenneth R. Boheler, +1

Circulation

Percutaneous left atrial appendage occlusion using different technologies in the United Kingdom: A multicenter registry

Timothy R. Betts, Milena Leo, Sandeep Panikker, +15

Catheterization and Cardiovascular Interventions

Acceleration of contraction by ?-adrenoceptor stimulation is greater in ventricular myocytes from failing than non-failing human hearts

Siân E. Harding, Lesley A. Brown, Federica del Monte, +5

Basic Research in Cardiology

MechanobiologyCardiac MuscleCardiomyopathyHeart FailureCardiac Mechanic +10

Transradial Secondary Arterial Access for Transcatheter Aortic Valve Implantation: Experience and Limitations

D. Wynne, Rajiv Rampat, Uday Trivedi, +4

Heart Lung and Circulation

Endovascular TechniqueVascular SurgerySurgeryVascular AccessEndovascular Management +6

Decreased contractile responses to isoproterenol in isolated cardiac myocytes from ageing guinea-pigs

Nicola Ferrara, P OGARA, D. Wynne, +3

Journal of Molecular and Cellular Cardiology

Animal PhysiologyCardiac MuscleCardiomyopathyHeart FailureMolecular Physiology +10

Radiation Dose During Percutaneous Treatment of Structural Heart Disease

J Boland, Louis W. Wang, Bernard J. Love, +2

Heart Lung and Circulation

Cardiovascular DiseaseRadiation TherapyRadiation DoseRadiation Therapy PlanningRadiation Effects +3

Incomplete reversal of β‐adrenoceptor desensitization in human and guinea‐pig cardiomyocytes by cyclic nucleotide phosphodiesterase inhibitors

D. Wynne, Philip A. Poole‐Wilson, Siân E. Harding

British Journal of Pharmacology