Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis

Xiaowei Wang, Christoph E. Hagemeyer, Jan David Hohmann, +7

Circulation

Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis

Xiaowei Wang, Yannik Gkanatsas, Jathushan Palasubramaniam, +5

Theranostics

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, +29

Nature Communications

Towards Effective and Safe Thrombolysis and Thromboprophylaxis

Xiaowei Wang, Jathushan Palasubramaniam, Yannik Gkanatsas, +10

Circulation Research

Evidence of Platelet Activation at Medically Used Hypothermia and Mechanistic Data Indicating ADP as a Key Mediator and Therapeutic Target

Andreas Straub, Stefanie Krajewski, Jan David Hohmann, +12

Arteriosclerosis Thrombosis and Vascular Biology

Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?

Jan David Hohmann, Xiaowei Wang, Stefanie Krajewski, +7

Blood

A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

M. Ziégler, Jan David Hohmann, Amy Searle, +4

European Heart Journal

Targeting Activated Platelets: A Unique and Potentially Universal Approach for Cancer Imaging

May Lin Yap, James D. McFadyen, Xiaowei Wang, +11

Theranostics

Dual-Targeted Theranostic Delivery of miRs Arrests Abdominal Aortic Aneurysm Development

Xiaowei Wang, Amy Searle, Jan David Hohmann, +9

Molecular Therapy

Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis: A Preclinical Pilot Study*

Tiago Granja, Andreas Körner, Christian Glück, +9

Critical Care Medicine