Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

Hanneke Schuitemaker, M. Koot, Neeltje A. Kootstra, +7

Journal of Virology

Primary ImmunodeficiencyBiological PhenotypeHiv-1 PopulationsHuman RetrovirusImmunology +13

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

Ron A. M. Fouchier, M Groenink, Neeltje A. Kootstra, +4

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyChemical BiologyHuman Retrovirus +19

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

M Tersmette, Rob A. Gruters, F. de Wolf, +6

Journal of Virology

Primary ImmunodeficiencyViral PersistenceNeurovirologyMedicinePathogenesis +11

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

M Tersmette, R E de Goede, Bert J. M. Al, +5

Journal of Virology

Primary ImmunodeficiencyViral ReplicationFrequent DetectionNeurovirologySyncytium-inducing Isolates +13

ASSOCIATION BETWEEN BIOLOGICAL PROPERTIES OF HUMAN IMMUNODEFICIENCY VIRUS VARIANTS AND RISK FOR AIDS AND AIDS MORTALITY

M Tersmette

The Lancet

Primary ImmunodeficiencySexual HealthHuman RetrovirusImmunologyGenetic Epidemiology +8

Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution

J J de Jong, Anthony de Ronde, Wilco Keulen, +2

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyViral Structural ProteinVirus Phenotype +15

Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture

Hanneke Schuitemaker, Neeltje A. Kootstra, R E de Goede, +3

Journal of Virology

T-regulatory CellImmunologyPathologyHiv-1 IsolatesImmunotherapy +15

Viral Phenotype and Immune Response in Primary Human Immunodeficiency Virus Type 1 Infection

Marijke Roos, Joep M. A. Lange, R E de Goede, +4

The Journal of Infectious Diseases

Primary ImmunodeficiencySi VariantsNineteen IndividualsMedicineHuman Retrovirus +13

Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity

J J de Jong, Jaap Goudsmit, Wilco Keulen, +4

Journal of Virology

Viral ReplicationSyncytium FormationImmunologyMolecular BiologyHiv-1 Isolates +14

Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages.

Hanneke Schuitemaker, Neeltje A. Kootstra, Marco Koppelman, +4

Journal of Clinical Investigation

Hiv-1 TranscriptionImmunologyImmune SystemImmunotherapyInflammation +15