T.C. Orton

Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats.

Peter Greaves, Rajiv Goonetilleke, Graham R. Nunn et al. · PubMed · 1993 · 303 citations

Medicine, Pharmacology, Toxicology +17

An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells

Oliver Flint, T.C. Orton · Toxicology and Applied Pharmacology · 1984 · 221 citations

Life Sciences, Anatomy, Developmental Biology +14

Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors.

Angus T. De Souza, Gerald R. Hankins, M. Kay Washington et al. · PubMed · 1995 · 190 citations

Medicine, Molecular Biology, Oncology +9

The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid.

T.C. Orton, Gerald L. Parker · Drug Metabolism and Disposition · 1982 · 162 citations

Medicine, Biochemistry, Pharmacology +15

Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man.

Christopher J. Rhodes, T.C. Orton, I. Pratt et al. · Environmental Health Perspectives · 1986 · 117 citations · Full text

Pharmacy, Pharmacokinetics, Toxicology +17