Functional improvement of jeopardized myocardium following intracoronary streptokinase infusion in acute myocardial infarction.

Richard S. Stack, Harry R. Phillips, Donald Grierson, +5

Journal of Clinical Investigation

Cardiac MuscleHeart FailureIntracoronary Streptokinase InfusionIntracoronary StreptokinaseCardiovascular Disease +12

Selective accumulation of the first component of complement and leukocytes in ischemic canine heart muscle. A possible initiator of an extra myocardial mechanism of ischemic injury.

Roger D. Rossen, J L Swain, Lloyd H. Michael, +3

Circulation Research

Cardiac MuscleHeart FailureImmunologyCardiovascular FunctionAcute Myocardial Infarction +22

The c-myc proto-oncogene regulates cardiac development in transgenic mice.

Twila A. Jackson, M. F. Allard, Catherine M. Sreenan, +3

Molecular and Cellular Biology

Cardiac MuscleC-myc ExpressionCardiac Progenitor CellsCardiac RegenerationEmbryology +14

Myoadenylate deaminase deficiency. Functional and metabolic abnormalities associated with disruption of the purine nucleotide cycle.

Richard L. Sabina, J L Swain, C. Warren Olanow, +4

Journal of Clinical Investigation

Muscle FunctionGeneticsMolecular BiologyAdenosine ContentMdd Patients +22

Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog.

Chaeseong Lim, Gregory D. Chapman, Roger Gammon, +4

Circulation

In Vivo Gene TherapyGene Therapy ApproachesBiomedical EngineeringPeripheral VasculaturesVivo Gene Transfer +17

Acidic fibroblast growth factor mRNA is expressed by cardiac myocytes in culture and the protein is localized to the extracellular matrix.

Howard L. Weiner, J L Swain

Proceedings of the National Academy of Sciences

Cardiac MuscleVascular GrowthFibrosisDevelopmental BiologyMolecular Physiology +13

Gene transfer into coronary arteries of intact animals with a percutaneous balloon catheter.

Gregory D. Chapman, Chaeseong Lim, Roger Gammon, +5

Circulation Research

EngineeringGeneticsGene DeliveryBiomedical EngineeringCardiovascular Translational Research +17

Metabolism of 5-amino-4-imidazolecarboxamide riboside in cardiac and skeletal muscle. Effects on purine nucleotide synthesis.

Richard L. Sabina, Kemp H. Kernstine, Robert L. Boyd, +2

Journal of Biological Chemistry

Cardiac MuscleBiochemistrySkeletal MuscleMedicinePhysiology +4

Accelerated repletion of ATP and GTP pools in postischemic canine myocardium using a precursor of purine de novo synthesis.

J L Swain, J. J. Hines, Richard L. Sabina, +1

Circulation Research

Gtp FallsCardiac MuscleCardiomyopathyHeart FailureMolecular Physiology +13

Repetitive episodes of brief ischaemia (12 min) do not produce a cumulative depletion of high energy phosphate compounds

J L Swain, R. L. Sabina, J. J. Hines, +2

Cardiovascular Research

Cardiac MuscleElectrolyte DisorderRepetitive EpisodesHematologyElectrolyte Disturbance +18