Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1

Maria E. González, X. Li, Kathy A. Toy, +6

Oncogene

Breast OncologyOncologyMedicineCancer GrowthCancer Cell Biology +7

EZH2 expands breast stem cells through activation of NOTCH1 signaling

Maria E. González, Heather M. Moore, Xin Li, +5

Proceedings of the National Academy of Sciences

Lineage PlasticityDevelopmental BiologyBreast Cancer InitiationTn Breast TicsSignaling Pathway +13

Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition

Yanhong Zhang, Kathy A. Toy, Celina G. Kleer

Modern Pathology

Epithelial-mesenchymal TransitionBreast OncologyTumor-initiating CellsMedicineMetaplastic Breast Carcinomas +8

Histone Methyltransferase EZH2 Induces Akt-Dependent Genomic Instability and BRCA1 Inhibition in Breast Cancer

Maria E. González, Matthew L. DuPrie, Heather Krueger, +4

Cancer Research

Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer

Kathy A. Toy, Rajeshwari R. Valiathan, Fernando M. Núñez, +4

Breast Cancer Research and Treatment

Breast OncologyMedicineReceptor Tyrosine KinaseBreast CancerTriple-negative Breast Cancer +8

EZH2 and ALDH-1 mark breast epithelium at risk for breast cancer development

Lakshmi P. Kunju, Cynthia Cookingham, Kathy A. Toy, +3

Modern Pathology

Tumor BiologyBreast OncologyCancer RiskMedicineBreast Cancer Development +7

RhoC Impacts the Metastatic Potential and Abundance of Breast Cancer Stem Cells

Devin T. Rosenthal, Jie Zhang, Liwei Bao, +5

PLoS ONE

CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer

Anupama Pal, Wei Huang, Xin Li, +3

Cancer Research

Breast OncologyP38 Map KinaseCancer BiologyCcn6 AttenuationMammary Gland Development +18

Invasive breast carcinomas in Ghana: high frequency of high grade, basal-like histology and high EZH2 expression

Judy Pang, Kathy A. Toy, Ken A. Griffith, +4

Breast Cancer Research and Treatment

Tumor BiologyBreast OncologyMedicinePathologyBreast Cancer +7

EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis

Heather M. Moore, Maria E. González, Kathy A. Toy, +3

Breast Cancer Research and Treatment

Ezh2 InhibitionBreast OncologyOncologyMedicineCancer Cell Biology +7