E. A. Newsholme

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

P J Randle, P. B. Garland, C. N. Hales et al. · The Lancet · 1963 · 5.1K citations

Obesity, Metabolic Syndrome, Biochemistry +10

Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles

Randle Pj, E. A. Newsholme, P. B. Garland · Biochemical Journal · 1964 · 736 citations · Full text

The activities of fructose 1,6-diphosphatase, phosphofructokinase and phosphoenolpyruvate carboxykinase in white muscle and red muscle

LH Opie, E. A. Newsholme · Biochemical Journal · 1967 · 375 citations · Full text

Inhibition of the Phosphofructokinase Reaction in Perfused Rat Heart by Respiration of Ketone Bodies, Fatty Acids and Pyruvate

E. A. Newsholme, P J Randle, Keith Manchester · Nature · 1962 · 295 citations

Cardiac Muscle, Energy Metabolism, Biochemistry +12

The maximum activities of hexokinase, phosphorylase, phosphofructokinase, glycerol phosphate dehydrogenases, lactate dehydrogenase, octopine dehydrogenase, phosphoenolpyruvate carboxykinase, nucleoside diphosphatekinase, glutamate-oxaloacetate transaminase and arginine kinase in relation to carbohydrate utilization in muscles from marine invertebrates

Victor A. Zammit, E. A. Newsholme · Biochemical Journal · 1976 · 238 citations · Full text

Biology, Animal Physiology, Energy Metabolism +15