Hippocampal Synapses Depend on Hippocampal Estrogen Synthesis

Oliver Kretz, Lars Fester, Uwe Wehrenberg, +8

Journal of Neuroscience

The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

Maria‐Magdalena Mocanu, Astrid Nissen, Katrin Eckermann, +10

Journal of Neuroscience

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

Astrid Sydow, Ann Van der Jeugd, Fang Zheng, +10

Journal of Neuroscience

The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy

Katrin Eckermann, Maria‐Magdalena Mocanu, Inna Khlistunova, +10

Journal of Biological Chemistry

Aromatase Inhibitors Induce Spine Synapse Loss in the Hippocampus of Ovariectomized Mice

Lepu Zhou, Lars Fester, Breda von Blittersdorff, +6

Endocrinology

Synapse FormationSpine Synapse FormationOvarian CancerSynapse LossNeurology +16

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

Janine Prange‐Kiel, Hubertus Jarry, Michael Schoen, +4

The Journal of Cell Biology

GynecologyHippocampal Estrogen SynthesisGnrh AntagonistsNeuroendocrine MechanismHealth Sciences +18

Cholesterol‐promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus

Lars Fester, Lepu Zhou, Andrea Bütow, +5

Hippocampus

Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons

Janine Prange‐Kiel, Lars Fester, Lepu Zhou, +3

Hippocampus

Neurodegeneration and <scp>NLRP3</scp> inflammasome expression in the anterior thalamus of <scp>SOD1(G93A) ALS</scp> mice

Berthold Debye, Lena Hanna Christine Schmülling, Lepu Zhou, +3

Brain Pathology

Als PathologySynaptic SignalingPrimary DegenerationSocial SciencesNeuroinflammation +22

Sex-Dependent Regulation of Aromatase-Mediated Synaptic Plasticity in the Basolateral Amygdala

Roland A. Bender, Lepu Zhou, Ricardo Vierk, +5

Journal of Neuroscience