The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells

C. Halbert, G W Demers, Denise A. Galloway

Journal of Virology

ImmunologyPathologyTumor BiologyHpv16 E7 GeneCancer-associated Virus +14

The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells

C. Halbert, G W Demers, Denise A. Galloway

Journal of Virology

Hpv GenesE7 GenesImmunologyPathologyTumor Biology +19

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

G W Demers, Scott A. Foster, C. Halbert, +1

Proceedings of the National Academy of Sciences

Cancer-associated VirusOncogenic AgentHpv16 E6Human Papillomavirus 16Pathology +12

Transduction by adeno-associated virus vectors in the rabbit airway: efficiency, persistence, and readministration

C. Halbert, T. A. Standaert, Moira L. Aitken, +3

Journal of Virology

Viral ReplicationAav TransductionPathogenesisImmunologyViral Pathogenesis +12

Motor and respiratory heterogeneity in Duchenne patients: Implication for clinical trials

Véronique Humbertclaude, Dalil Hamroun, Kamel Bezzou, +29

European Journal of Paediatric Neurology

MedicineRespiratory NeurobiologyPhysiologyClinical TrialsMotor Control +9

Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells

C. Halbert, Ian E. Alexander, Greg Wolgamot, +1

Journal of Virology

Viral ReplicationSynthetic VirologyImmunologyTransduction EfficiencyCellular Physiology +16

Immortalization of primary human smooth muscle cells.

Nuria Perez‐Reyes, C. Halbert, Patricia P. Smith, +2

Proceedings of the National Academy of Sciences

Muscle PhysiologyMuscle FunctionCancer-associated VirusSkeletal MuscleMedicine +11

Identification of the E5 open reading frame of human papillomavirus type 16

C. Halbert, Denise A. Galloway

Journal of Virology

Viral DiagnosticsSynthetic VirologyImmunologyPathologyMolecular Genetics +14

Expression of the HPV16 E7 gene generates proliferation in stratified squamous cell cultures which is independent of endogenous p53 levels.

R A Blanton, Marc D. Coltrera, A M Gown, +2

PubMed

Viral ReplicationImmunologyPathologyCell ProliferationTumor Biology +14

Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production

C. Halbert, Michael J. Metzger, S.K. Lam, +1

Gene Therapy

Vector ProductionNatural SciencesGeneticsGenetic EngineeringMolecular Biology +11