Microparticles: major transport vehicles for distinct microRNAs in circulation

Philipp Diehl, Alba Fricke, Laura Sander, +8

Cardiovascular Research

Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction

Jonathon Habersberger, Frederik Strang, Amelie Scheichl, +9

Cardiovascular Research

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, +29

Nature Communications

Increased levels of circulating microparticles in patients with severe aortic valve stenosis

Verena Sossong, Thomas Helbing, Friedhelm Beyersdorf, +5

Thrombosis and Haemostasis

Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension

Philipp Diehl, Miriam Aleker, Thomas Helbing, +5

Journal of Thrombosis and Thrombolysis

InflammationThrombosisThrombopoiesisPulmonary Arterial HypertensionCardiovascular Disease +12

Enhanced microparticles in ventricular assist device patients predict platelet, leukocyte and endothelial cell activation

Philipp Diehl, Miriam Aleker, Thomas Helbing, +5

Interactive Cardiovascular and Thoracic Surgery

Bleeding ComplicationsHeart FailureEnhanced MicroparticlesDevice TherapyPlatelet Dysfunction +16

Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes

Philipp Diehl, Christoph B. Olivier, Christoph Halscheid, +3

Basic Research in Cardiology

InflammationThrombosisPlatelet Aggregation InhibitorsThrombopoiesisBlood Platelet +10

P2Y12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells

Patrick M. Siegel, Laura Sander, Alba Fricke, +11

Scientific Reports

Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability

Philipp Diehl, Frederik Nienaber, Maria T. K. Zaldivia, +18

Thrombosis and Haemostasis

Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis

Christoph Koentges, María Cecilia Cimolai, Katharina Pfeil, +11

Journal of Molecular and Cellular Cardiology

Reductive StressSignal TransductionMolecular PhysiologyBiochemistryPhysiology +12