Kung Wen Lu

Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells.

Hsu Feng Lu, Yi Shan Chen, Jai‐Sing Yang et al. · PubMed · 2008 · 73 citations

Chemoprevention Strategy, Gynostemma Pentaphyllum Makino, Apoptosis +17

Gypenosides inhibited invasion and migration of human tongue cancer SCC4 cells through down-regulation of NFkappaB and matrix metalloproteinase-9.

Kung Wen Lu, Ming Li Tsai, Jung Chou Chen et al. · PubMed · 2008 · 59 citations

Pathology, Cell Death, Cell Proliferation +18

Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3.

Jung Chou Chen, Kung Wen Lu, Jau Hong Lee et al. · PubMed · 2007 · 55 citations

Chemoprevention Strategy, Apoptosis, Pathology +19

Inhibition of invasion and migration by newly synthesized quinazolinone MJ-29 in human oral cancer CAL 27 cells through suppression of MMP-2/9 expression and combined down-regulation of MAPK and AKT signaling.

Chi‐Cheng Lu, Jai‐Sing Yang, Jo Hua Chiang et al. · PubMed · 2012 · 30 citations

Cal 27, Oncology, Akt Signaling +15

α-Phellandrene alters expression of genes associated with DNA damage, cell cycle, and apoptosis in murine leukemia WEHI-3 cells.

Jen Jyh Lin, Chien Chih Yu, Kung Wen Lu et al. · PubMed · 2014 · 14 citations

Transcriptional Regulation, Plant Gene Expression, Dna Damage +15