William D. Holmes

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

Nathalie Signoret, Joanne Oldridge, Annegret Pelchen–Matthews et al. · The Journal of Cell Biology · 1997 · 384 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +15

Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity

Robert X. Xu, Anne M. Hassell, Dana E. Vanderwall et al. · Science · 2000 · 334 citations

Life Sciences, Biochemistry, Molecular Biology +17

Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A

Eric B. Fauman, John Cogswell, Brett Lovejoy et al. · Cell · 1998 · 283 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis

H. Neal Bramson, J. Corona, Stephen T. Davis et al. · Journal of Medicinal Chemistry · 2001 · 271 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor:  X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kinase

Lisa M. Shewchuk, Anne M. Hassell, Bruce Wisely et al. · Journal of Medicinal Chemistry · 1999 · 236 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17