William D. Holmes - Concepedia

Concepedia

Author

William D. Holmes

Research Triangle Park Foundation

Also Known As

W Holmes, W. D. Holmes, W. Holmes, W.D Holmes, W.D. Holmes, William D Holmes, William D. HOLMES, William D. Holmes, William Holmes

33

Publications

2.2K

Citations

16

H-Index

51

Concepts

All Affiliations

Research Triangle Park Foundation Howard Hughes Medical Institute GlaxoSmithKline (United States)

WD

About

William D. Holmes is an author at Research Triangle Park Foundation specializing in medicine, biochemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	13	1.6K
2	Biochemistry	9	9	1.3K
3	Natural Sciences	8	8	1.3K
4	Public Health	1	1	28
5	Anesthesia	1	1	17

William D. Holmes

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17

Publications

2.2K

Citations

16

H-Index

	Year	Citations
Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4 Nathalie Signoret, Joanne Oldridge, Annegret Pelchen–Matthews, The Journal of Cell Biology	1997	384
Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity Robert X. Xu, Anne M. Hassell, Dana E. Vanderwall, Science Proteinlipid InteractionCyclic NucleotidesCatalytic DomainBiochemistryProtein Assembly	2000	332
Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A Eric B. Fauman, John Cogswell, Brett Lovejoy, Cell Crystal StructureCatalytic DomainSignal TransductionCellular EnzymologyBiochemistry	1998	282
Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2): Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis H. Neal Bramson, J. Corona, Stephen T. Davis, Journal of Medicinal Chemistry Oxindole-based InhibitorsOxindole-based CompoundsLigand DockingCell CycleHeterocycle Chemistry	2001	267
Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor: X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kinase Lisa M. Shewchuk, Anne M. Hassell, Bruce Wisely, Journal of Medicinal Chemistry Medicinal ChemistryDrug TargetBiochemistry4-Anilinoquinazolines RepresentNatural Sciences	1999	231
Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors Stephen T. Davis, Bill Benson, H. Neal Bramson, Science Cdk InhibitorsChemoprevention StrategyHair LossMedicinePharmacology	2001	167
Structure of the Tie2 RTK Domain Lisa M. Shewchuk, Anne M. Hassell, Byron Ellis, Structure Computational TopologyTie2 Rtk Domain	2000	145
Human Recombinant Phosphodiesterase 4B2B Binds (<i>R</i>)-Rolipram at a Single Site with Two Affinities Warren J. Rocque, Gaochao Tian, Jeffrey S. Wiseman, Biochemistry Proteinlipid InteractionAmino AcidsProtein AssemblyMolecular Biology-Rolipram Binding	1997	69
Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase James M. Lenhard, Daniel B. Kassel, Warren J. Rocque, Biochemical Journal Protein FunctionMolecular PhysiologySignal TransductionBiochemistryHspde4b2b Conform	1996	55
Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding Warren J. Rocque, William D. Holmes, Indravadan R. Patel, Protein Expression and Purification Proteinlipid InteractionProtein FunctionDetailed CharacterizationPurified Type 4Biochemistry	1997	45

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