P Chapman

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Melissa B. Pappalardi, Kathryn Keenan, Mark Cockerill et al. · Nature Cancer · 2021 · 251 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +9

Differential gene expression between Zucker Fatty rats and Zucker Diabetic Fatty rats: a potential role for the immediate-early gene Egr-1 in regulation of beta cell proliferation

Kay E. Garnett, P Chapman, Julie A. Chambers et al. · Journal of Molecular Endocrinology · 2005 · 46 citations · Full text

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity

Rebecca Newton, Katherine A. Bowler, Emily M. Burns et al. · European Journal of Medicinal Chemistry · 2016 · 38 citations · Full text

Combinatorial Chemistry, Drug Target, Pharmacotherapy +16

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Obbina Abani, Amr E. Abbas, Fatima Abbas et al. · The Lancet Diabetes & Endocrinology · 2023 · 34 citations · Full text

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial

Saul N. Faust, Richard Haynes, Christine E. Jones et al. · The Lancet Child & Adolescent Health · 2024 · 31 citations · Full text