Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

Raymonda Varon, Christine Vissinga, Matthias Platzer, +16

Cell

Is MutatedChromatinGenome InstabilityGenetic DisorderNatural Sciences +8

The CUB Domain

Peer Bork, Georg Beckmann

Journal of Molecular Biology

Domain TheoryComputer ScienceDiscrete MathematicsCub DomainComputational Topology

Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)

Quangeng Zhang, Reiner Siebert, Minhong Yan, +16

Nature Genetics

Lymphoid NeoplasiaImmunologyPathologyMalt LymphomaAdult T-cell Leukemia-lymphoma +3

AKT1 E17K mutation profiling in breast cancer: prevalence, concurrent oncogenic alterations, and blood-based detection

Marion Rudolph, Tobias Anzeneder, Anke Schulz, +8

BMC Cancer

Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins 1 1Edited by G. Von Heijne

Georg Beckmann, Jens Hanke, Peer Bork, +1

Journal of Molecular Biology

Protein FunctionBiochemistryProtein AssemblyProtein FoldingFold Prediction +10

Exon Array Analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer

Wolfram Langer, Florian Sohler, Gabriele Leder, +5

BMC Genomics

Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymphoma

Georg Lenz, Eliza A. Hawkes, Gregor Verhoef, +16

Leukemia

Abc DlbclImmunologyPathologySingle-agent ActivityPharmacotherapy +18

EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes

Henar Hernando, Kathy A. Gelato, Ralf Lesche, +5

Molecular Cancer Therapeutics

Alzheimer Amyloid Peptide Aβ42 Regulates Gene Expression of Transcription and Growth Factors

Christian Barucker, Anette Sommer, Georg Beckmann, +12

Journal of Alzheimer s Disease

Neurochemical BiomarkersRobust BiomarkersSynaptic SignalingSocial SciencesNeuroinflammation +22

Molecular profiles and clinical outcome of stage UICC II colon cancer patients

Jörn Gröne, Dido Lenze, Vindi Jurinović, +11

International Journal of Colorectal Disease

Gastrointestinal OncologyMedicineGastroenterologyColorectal CancerPathology +7