Philip M. Dean

WaterScore: a novel method for distinguishing between bound and displaceable water molecules in the crystal structure of the binding site of protein-ligand complexes

Alfonso T. García‐Sosa, Ricardo L. Mancera, Philip M. Dean · Journal of Molecular Modeling · 2003 · 128 citations

Protein Chemistry, Crystal Structure, Protein-ligand Complexes +11

A validation study on the practical use of automated de novo design

Martin Ståhl, Nikolay P. Todorov, Tim James et al. · Journal of Computer-Aided Molecular Design · 2002 · 79 citations

Receptor Flexibility in de Novo Ligand Design and Docking

Ian L. Alberts, Nikolay P. Todorov, Philip M. Dean · Journal of Medicinal Chemistry · 2005 · 64 citations · Full text

Protein Assembly, Molecular Biology, Protein Folding +16

Scaffold Hopping in De Novo Design. Ligand Generation in the Absence of Receptor Information

David G. Lloyd, Christoph L. Buenemann, Nikolay P. Todorov et al. · Journal of Medicinal Chemistry · 2003 · 62 citations

Engineering, Estrogen Receptor, Molecular Biology +20

Efficient Conformational Sampling of Local Side-chain Flexibility

Per Källblad, Philip M. Dean · Journal of Molecular Biology · 2003 · 54 citations

Geometric Modeling, Local Side-chain Flexibility, Engineering +10