Stimulation of new bone formation by direct transfer of osteogenic plasmid genes.

Jianmin Fang, Yaqin Zhu, Elizabeth Smiley, +6

Proceedings of the National Academy of Sciences

Tissue EngineeringEngineeringParathyroid Hormone FragmentBone RepairOsteogenesis +18

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices

Hao Zhang, Weiguo Hu, EC Davis, +4

The Journal of Cell Biology

Fbn2 Gene ProductEngineeringCell AdhesionMolecular BiologyCytoskeleton +22

Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome

Lygia V. Pereira, Marina D’Alessio, Francesco Ramirez, +4

Human Molecular Genetics

Altered triple helical structure of type I procollagen in lethal perinatal osteogenesis imperfecta.

J Bonadio, K A Holbrook, Richard Gelinas, +2

Journal of Biological Chemistry

Transgenic mouse model of the mild dominant form of osteogenesis imperfecta.

J Bonadio, Thomas L. Saunders, Emily J. Tsai, +7

Proceedings of the National Academy of Sciences

Mild Dominant FormBone FragilityPathologyOsteogenesisTransgenic Mouse Model +18

Osteoporosis induced in mice by overproduction of interleukin 4.

David B. Lewis, H. Denny Liggitt, E L Effmann, +7

Proceedings of the National Academy of Sciences

InflammationBone DiseaseSclerostinDevelopmental BiologyAutoimmune Disease +12

Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation.

Vijay Baragi, Richard R. Renkiewicz, H Jordan, +3

Journal of Clinical Investigation

Tissue EngineeringEngineeringImmunologyBone RepairBiomedical Engineering +23

Intron-mediated recombination may cause a deletion in an alpha 1 type I collagen chain in a lethal form of osteogenesis imperfecta.

Gregory S. Barsh, C L Roush, J Bonadio, +2

Proceedings of the National Academy of Sciences

SclerostinGeneticsBone RepairOsteogenesisMolecular Genetics +18

A murine skeletal adaptation that significantly increases cortical bone mechanical properties. Implications for human skeletal fragility.

J Bonadio, Karl J. Jepsen, Monique K. Mansoura, +3

Journal of Clinical Investigation

Bending StrengthBone RepairOsteogenesisOsteoporosisOrthopaedic Surgery +22

A DNA Controlled-Release Coating for Gene Transfer: Transfection in Skeletal and Cardiac Muscle

Vinod Labhasetwar, J Bonadio, Steven A. Goldstein, +1

Journal of Pharmaceutical Sciences