Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.

T A McCaffrey, D J Falcone, Cory Brayton, +3

The Journal of Cell Biology

ImmunologyCell GrowthCellular PhysiologyThrombosisAngiogenesis +20

Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells.

D P Hajjar, Babette B. Weksler, D J Falcone, +3

Journal of Clinical Investigation

Lipid PeroxidationCyclic Adenosine MonophosphateInjured Rabbit AortaCellular PhysiologyOxidative Stress +16

Decreased type II/type I TGF-beta receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-beta1.

T A McCaffrey, Seth Consigli, D J Falcone, +3

Journal of Clinical Investigation

Vascular DiseaseImmunologyPathologyProfibrotic ResponseCellular Physiology +17

Recovery of prostacyclin production by de-endothelialized rabbit aorta. Critical role of neointimal smooth muscle cells.

Amiram Eldor, D J Falcone, D P Hajjar, +2

Journal of Clinical Investigation

Vascular DiseaseSynthetic CapacityBiomedical EngineeringDe-endothelialized Rabbit AortaCellular Physiology +19

Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation

D J Falcone, Timothy A. McCaffrey, Adriana Haimovitz‐Friedman, +2

Journal of Biological Chemistry

Cell AdhesionImmunologyCell ProliferationCytoskeletonCell Growth +18

Insoluble low-density lipoprotein-proteoglycan complexes enhance cholesteryl ester accumulation in macrophages.

Brian Salisbury, D J Falcone, C R Minick

PubMed

Herpes simplex virus infection in human arterial cells. Implications in arteriosclerosis.

D P Hajjar, Kenneth B. Pomerantz, D J Falcone, +2

Journal of Clinical Investigation

Vascular DiseaseViral PathogenesisImmunologyPathologyInflammation +18

Endothelium modifies the altered metabolism of the injured aortic wall.

D P Hajjar, D J Falcone, S Fowler, +1

PubMed

Lipoprotein-heparin-fibronectin-denatured collagen complexes enhance cholesteryl ester accumulation in macrophages.

D J Falcone, N Mated, H Shio, +2

The Journal of Cell Biology

InflammationVascular Extracellular MatrixBiochemistryLipid AccumulationNatural Sciences +11

Periprostatic adipose inflammation is associated with high-grade prostate cancer

Ayca Gucalp, Neil M. Iyengar, Xi Kathy Zhou, +16

Prostate Cancer and Prostatic Diseases

ObesityMetabolic SyndromeUrologyPeriprostatic Adipose InflammationPerineural Invasion +4