An oxidative DNA “damage” and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression

Viktor Pastukh, Justin T. Roberts, David W. Clark, +5

American Journal of Physiology-Lung Cellular and Molecular Physiology

Dna DamageRedox BiologyOxidative StressTranscriptional RegulationRedox Regulator +16

Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis

Craig Ricci, Viktor Pastukh, Joshua N. Leonard, +4

American Journal of Physiology-Cell Physiology

Dna DamageMitochondrial FunctionBiochemistryNatural SciencesApoptosis +12

Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes

Mikhail Alexeyev, N. I. Venediktova, Viktor Pastukh, +3

Gene Therapy

Mitochondrial MyopathyMitophagyMitochondrial BiogenesisMitochondrial FunctionGenetic Disorder +10

Apoptotic cascade initiated by angiotensin II in neonatal cardiomyocytes: role of DNA damage

Valentina Grishko, Viktor Pastukh, Viktoriya Solodushko, +3

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleHeart FailureDna DamageNadph OxidaseNitric Oxide +22

Role of protein phosphorylation in excitation-contraction coupling in taurine deficient hearts

K. C. Ramila, Chian Ju Jong, Viktor Pastukh, +3

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleHeart FailureTaurine DeficiencyCardiovascular FunctionCellular Physiology +20

Sequence-specific oxidative base modifications in hypoxia-inducible genes

Viktor Pastukh, Mykhaylo V. Ruchko, Olena M. Gorodnya, +2

Free Radical Biology and Medicine

BiochemistryRedox RegulatorNatural SciencesGeneticsHypoxia (Medicine) +5

Oxidative DNA Modifications in Hypoxic Signaling

Mark N. Gillespie, Viktor Pastukh, Mykhaylo V. Ruchko

Annals of the New York Academy of Sciences

Molecular BiologyReactive Oxygen SpeciesRedox BiologyOxidative StressTranscriptional Regulation +14

Contribution of the PI 3-kinase/Akt survival pathway toward osmotic preconditioning

Viktor Pastukh, Craig Ricci, Viktoriya Solodushko, +2

Molecular and Cellular Biochemistry

Signal TransductionMolecular PhysiologyMedicineReceptor Tyrosine KinaseCell Death +7

Possible Cause of Taurine-deficient Cardiomyopathy: Potentiation of Angiotensin II Action

Stephen W. Schaffer, Viktoriya Solodushko, Viktor Pastukh, +2

Journal of Cardiovascular Pharmacology

Cardiac MuscleHeart FailureImmunologyCell DeathTaurine Deficiency +14

The Functionality of Minimal PiggyBac Transposons in Mammalian Cells

Boris Troyanovsky, Vira Bitko, Viktor Pastukh, +2

Molecular Therapy — Nucleic Acids