A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity

Noriaki Endo, Naoji Umemoto, Yoshinori Katō, +2

Journal of Immunological Methods

Amino GroupsBiochemistryNovel Covalent ModificationProtein FoldingNatural Sciences +10

The relation between health literacy, hypertension knowledge, and blood pressure among middle-aged Japanese adults

Akiko Shibuya, Ryusuke Inoue, Takayoshi Ohkubo, +4

Blood Pressure Monitoring

A novel method of conjugation of daunomycin with antibody with a poly(L-glutamic acid) derivative as intermediate drug carrier. An anti-.alpha.-fetoprotein antibody-daunomycin conjugate

Yoshinori Katō, Naoji Umemoto, Yasutaka Kayama, +4

Journal of Medicinal Chemistry

In vitro cytotoxicity of a human serum albumin-mediated conjugate of methotrexate with anti-MM46 monoclonal antibody.

Noriaki Endo, Yoshinori Katō, Yumiko Takeda, +4

PubMed

Medicinal ChemistryMurine Monoclonal AntibodyImmunotoxicologyMedicineAnti-mm46 Monoclonal Antibody +13

Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge

Yoshio Takeda, Hitoshi Togashi, Taku Matsuo, +3

Journal of Gastroenterology

Chemoprevention StrategyMedicineApoptosisGrowth InhibitionCell Death +6

Antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugated with polyglutamic acid and its derivative.

Yoshinori Katō, Masahiko Saito, Hisashi Fukushima, +2

PubMed

Pharmaceutical ScienceBioorganic ChemistryAntitumor ActivityPolyglutamic AcidGlycobiology +16

Target-selective cytotoxicity of methotrexate conjugated with monoclonal anti-MM46 antibody

Noriaki Endo, Yumiko Takeda, Kazuo Kishida, +4

Cancer Immunology Immunotherapy

ImmunologyMonoclonal Anti-mm46 AntibodyImmunochemistryAntibody EngineeringImmunotherapy +2

Nature of linkage and mode of action of methotrexate conjugated with antitumor antibodies: implications for future preparation of conjugates.

Noriaki Endo, Yumiko Takeda, Naoji Umemoto, +5

PubMed

Inhibitory ActivityDrug TargetingOncologyDirect Mtx ConjugateMedicine +12

Preparation and <i>in vitro</i> cytotoxicity of a methotrexate‐anti‐MM46 monoclonal antibody conjugate <i>via</i> an oligopeptide spacer

Naoji Umemoto, Yoshinori Katō, Noriaki Endo, +2

International Journal of Cancer

Drug TargetingOncologyOligopeptide SpacerMedicineMetronomic Therapy +13

Description of the interaction between Candida albicans and macrophages by mixed and quantitative proteome analysis without isolation

Nao Kitahara, Hironobu Morisaka, Wataru Aoki, +4

AMB Express

Proteomic TechnologyBiochemistryMicrobial PathogensCandida AlbicansMedicine +13