J.A. Castro

Prevention of carbon tetrachloride-induced necrosis by inhibitors of drug metabolism—Further studies on their mechanism of action

J.A. Castro, E.C. de Ferreyra, C.R. de Castro et al. · Biochemical Pharmacology · 1974 · 130 citations

Biochemistry, Medicine, Carbon Tetrachloride-induced Necrosis +9

Toxic effects of nifurtimox and benznidazole, two drugs used against American trypanosomiasis (Chagas' disease).

J.A. Castro, E G Diaz de Toranzo · PubMed · 1988 · 129 citations

Irreversible binding of 14C from 14CCl4 to liver microsomal lipids and proteins from rats pretreated with compounds altering microsomal mixed-function oxygenase activity

M.I. Díaz Gómez, J.A. Castro, E.C. de Ferreyra et al. · Toxicology and Applied Pharmacology · 1973 · 78 citations

Chemical Biology, Oxysterol, Biochemistry +12

Interaction of benznidazole reactive metabolites with nuclear and kinetoplastic DNA, proteins and lipids fromTrypanosoma cruzi

Edith G.D. de Toranzo, J.A. Castro, Berta M. Franke de Cazzulo et al. · Cellular and Molecular Life Sciences · 1988 · 78 citations

Biochemistry, Kinetoplastic Dna, Medicine +7

Mechanisms of the preventive properties of some garlic components in the carbon tetrachloride-promoted oxidative stress. Diallyl sulfide; diallyl disulfide; allyl mercaptan and allyl methyl sulfide.

Silvia Laura Fanelli, G.D. Castro, E G de Toranzo et al. · PubMed · 1998 · 66 citations

Allyl Methyl Sulfide, Lipid Peroxidation, Redox Biology +16