Mosi Lin

Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1

Vivek Patel, Katelyn Dial, Jiaqi Wu et al. · International Journal of Molecular Sciences · 2020 · 73 citations · Full text

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation

Ravikumar Sitapara, Alex Gauthier, Sergio Iván Valdés‐Ferrer et al. · Molecular Medicine · 2020 · 43 citations · Full text

The nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised innate immunity in bacterial clearance in a mouse model of ventilator-associated pneumonia

Ashwini Gore, Alex Gauthier, Mosi Lin et al. · Biochemical Pharmacology · 2020 · 17 citations · Full text

Asthma, Inflammation, Reactive Nitrogen Specie +11

GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

Ravikumar Sitapara, Alex Gauthier, Vivek Patel et al. · Molecular Medicine · 2020 · 14 citations · Full text

The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages

Alex Gauthier, Jiaqi Wu, Mosi Lin et al. · Antioxidants · 2021 · 11 citations · Full text