Deep Learning–Based Segmentation and Quantification in Experimental Kidney Histopathology

Nassim Bouteldja, Barbara M. Klinkhammer, Roman D. Bülow, +15

Journal of the American Society of Nephrology

Mapping the cardiac vascular niche in heart failure

Fabian Peisker, Maurice Halder, James S. Nagai, +13

Nature Communications

Empagliflozin improves left ventricular diastolic function of db/db mice

Julia Moellmann, Barbara M. Klinkhammer, Patrick Droste, +11

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Heart FailureMedicinePhysiologyCardiovascular FunctionPharmacology +3

Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy

Julia Moellmann, Barbara M. Klinkhammer, Julia Onstein, +8

Diabetes

Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease

Yaoxian Xu, Christoph Kuppe, Javier Perales-Patón, +36

Nature Genetics

GlomerulonephritisUrologyAdvanced ModelMedicineRenal Pathology +9

Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction

Florian Kahles, Marcia Viviane Rückbeil, R. Mertens, +9

European Heart Journal

The sodium‐glucose co‐transporter‐2 inhibitor ertugliflozin modifies the signature of cardiac substrate metabolism and reduces cardiac <scp>mTOR</scp> signalling, endoplasmic reticulum stress and apoptosis

Julia Moellmann, Pascal Alexander Mann, Ben A. Kappel, +8

Diabetes Obesity and Metabolism

Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine Cardiomyocytes

Lukas Märtin, Carsten Peters, Susanne Schmitz, +7

Shock

Heart FailureMitochondrial DysfunctionLipid PeroxidationCellular PhysiologyOxidative Stress +16

Sinks in patient rooms in ICUs are associated with higher rates of hospital-acquired infection: a retrospective analysis of 552 ICUs

Giovanni-Battista Fucini, Christine Geffers, F. Schwab, +4

Journal of Hospital Infection

Patient RoomsHospital-acquired InfectionHealthcare-associated InfectionClinical EpidemiologyPatient Safety +6

Myocardial infarction is sufficient to increase GLP‐1 secretion, leading to improved left ventricular contractility and mitochondrial respiratory capacity

Sebastian Diebold, Julia Moellmann, Florian Kahles, +7

Diabetes Obesity and Metabolism

Cardiac MuscleHeart FailureGlp‐1 SecretionAcute Myocardial InfarctionMetabolic Syndrome +14