Heather F. Bigg - Concepedia

Author

Heather F. Bigg

University of British Columbia

Also Known As

H Bigg, H F Bigg, H.F Bigg, H.F. Bigg, HEATHER F. BIGG, Heather Bigg, Heather F Bigg, Heather F. Bigg

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

University of British Columbia Addenbrooke's Hospital Newcastle University Roswell Park Comprehensive Cancer Center

About

Heather F. Bigg is an author at University of British Columbia specializing in medicine, cell biology, and matrix biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	627
2	Natural Sciences	3	3	437
3	Biochemistry	3	3	324
4	Engineering	1	1	32
5	Allergy	1	1	33

Heather F. Bigg

Publications

1.6K

Citations

H-Index

Page 1

	Year	Citations
Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels S H Ridley, S J Sarsfield, J C Lee, The Journal of Immunology	1997	285
Cellular Activation of MMP-2 (Gelatinase A) by MT2-MMP Occurs via a TIMP-2-independent Pathway Charlotte Morrison, Georgina S. Butler, Heather F. Bigg, Journal of Biological Chemistry	2001	179
Specific, High Affinity Binding of Tissue Inhibitor of Metalloproteinases-4 (TIMP-4) to the COOH-terminal Hemopexin-like Domain of Human Gelatinase A Heather F. Bigg, Y. Eric Shi, Yiliang E. Liu, Journal of Biological Chemistry Human Gelatinase AImmunologyHigh Affinity BindingCytoskeletonCellular Physiology	1997	159
Activity of matrix metalloproteinase‐9 against native collagen types I and III Heather F. Bigg, Andrew D. Rowan, Michael D. Barker, FEBS Journal	2007	157
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase. Heather F. Bigg, Charlotte Morrison, Georgina S. Butler, PubMed ImmunologyCell ProliferationGelatinase AMetalloproteinases-4 InhibitsCellular Physiology	2001	144
The Mammalian Chitinase-like Lectin, YKL-40, Binds Specifically to Type I Collagen and Modulates the Rate of Type I Collagen Fibril Formation Heather F. Bigg, Robin Wait, Andrew D. Rowan, Journal of Biological Chemistry	2006	138
Tissue Inhibitor of Metalloproteinase (TIMP)-2 Acts Synergistically with Synthetic Matrix Metalloproteinase (MMP) Inhibitors but Not with TIMP-4 to Enhance the (Membrane Type 1)-MMP-dependent Activation of Pro-MMP-2 Márta Tóth, M. Margarida Bernardo, David C. Gervasi, Journal of Biological Chemistry Synthetic Matrix MetalloproteinaseCancer BiologyCellular PhysiologyTumor BiologyPro-mmp-2 Activation	2000	134
Domain Interactions in the Gelatinase A·TIMP-2·MT1-MMP Activation Complex Christopher M. Overall, Eric M. Tam, G. Angus McQuibban, Journal of Biological Chemistry	2000	96
The Involvement of the Fibronectin Type II-like Modules of Human Gelatinase A in Cell Surface Localization and Activation Bjorn Steffensen, Heather F. Bigg, Christopher M. Overall Journal of Biological Chemistry	1998	90
Identification, regulation and role of tissue inhibitor of metalloproteinases‐4 (TIMP‐4) in human platelets Anna Radomski, Paul Jurasz, Esmond J. Sanders, British Journal of Pharmacology ImmunologyPathologyPlatelet PathobiologyPharmacotherapyMetronomic Chemotherapy	2002	81

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