William M. Watkins

Sequence Variation of the Hydroxymethyldihydropterin Pyrophosphokinase: Dihydropteroate Synthase Gene in Lines of the Human Malaria Parasite, <i>Plasmodium falciparum</i>, with Differing Resistance to Sulfadoxine

Darren R. Brooks, Ping Wang, Martin Read et al. · European Journal of Biochemistry · 1994 · 372 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

Ping Wang, Chung-Shinn Lee, Riad Bayoumi et al. · Molecular and Biochemical Parasitology · 1997 · 260 citations

Life Sciences, Genetics, Molecular Genetics +16

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania

Theonest K. Mutabingwa, Alexis Nzila, E.K. Mberu et al. · The Lancet · 2001 · 179 citations

Pharmacy, Pharmacology, Pharmacotherapy +12

Synergistic Antimalarial Activity of Pyrimethamine and Sulfadoxine against Plasmodium falciparum In Vitro

Jeffrey D. Chulay, William M. Watkins, David Sixsmith · American Journal of Tropical Medicine and Hygiene · 1984 · 138 citations

Medicine, Pharmacology, Antimicrobial Pharmacology +16

Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long‐Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter‐Acting Chlorproguanil/Dapsone on Kenyan<i>Plasmodium falciparum</i>

Alexis Nzila, Eunice Nduati, E.K. Mberu et al. · The Journal of Infectious Diseases · 2000 · 135 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17