Barry Coyle

Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes

Barry Coyle, Kevin Kavanagh, Malachy McCann et al. · BioMetals · 2003 · 145 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]·2H2O, [Cu(phen)2(mal)]·2H2O and [Mn(phen)2(mal)]·2H2O (malH2=malonic acid) using human cancer cells

C. Deegan, Malachy McCann, Michael Devereux et al. · Cancer Letters · 2006 · 113 citations

Medicine, Oncology, Pharmacology +10

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes

Barry Coyle, Paula Kinsella, Malachy McCann et al. · Toxicology in Vitro · 2003 · 108 citations

Life Sciences, Biochemistry, Cell Biology +11

In vitro anti-tumour effect of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)3](ClO4)2·4H2O and [Ag(phendione)2]ClO4 using human epithelial cell lines

C. Deegan, Barry Coyle, Malachy McCann et al. · Chemico-Biological Interactions · 2006 · 101 citations

Medicine, Oncology, Pharmacology +10

Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells

Malachy McCann, Barry Coyle, Sinead McKay et al. · BioMetals · 2004 · 94 citations

Natural Sciences, Biochemistry, Chemistry +11