Nuran Koçak

Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology

Mukesh Gautam, Javier H. Jara, Nuran Koçak et al. · Acta Neuropathologica · 2018 · 79 citations

Life Sciences, Neurobiology, Neuroscience +17

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Javier H. Jara, Mukesh Gautam, Nuran Koçak et al. · Journal of Neuroinflammation · 2019 · 59 citations · Full text

Medicine, Neurology, Neuroscience +17

Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS

Mukesh Gautam, Edward Xie, Nuran Koçak et al. · Frontiers in Cellular Neuroscience · 2019 · 37 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology

Barış Genç, Mukesh Gautam, Öge Gözütok et al. · Clinical and Translational Medicine · 2021 · 33 citations · Full text

Life Sciences, Neurology, Neuroscience +17

SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function

Mukesh Gautam, Barış Genç, Benjamin Helmold et al. · Neurobiology of Disease · 2023 · 29 citations · Full text

Life Sciences, Neurology, Neuroscience +17