Michael S. Bobola

The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.

John R. Silber, Michael S. Bobola, A. Blank et al. · PubMed · 2002 · 149 citations

Medicine, Molecular Biology, Oncology +16

O6-Methylguanine-DNA Methyltransferase, O6-Benzylguanine, and Resistance to Clinical Alkylators in Pediatric Primary Brain Tumor Cell Lines

Michael S. Bobola, John R. Silber, Richard G. Ellenbogen et al. · Clinical Cancer Research · 2005 · 110 citations

Medicine, Oncology, Pharmacology +17

Apurinic/Apyrimidinic Endonuclease Activity Is Associated with Response to Radiation and Chemotherapy in Medulloblastoma and Primitive Neuroectodermal Tumors

Michael S. Bobola, Laura S. Finn, Richard G. Ellenbogen et al. · Clinical Cancer Research · 2005 · 103 citations

Medicine, Oncology, Radiation Oncology +17

Apurinic Endonuclease Activity in Adult Gliomas and Time to Tumor Progression after Alkylating Agent-Based Chemotherapy and after Radiotherapy

Michael S. Bobola, Mary J. Emond, A. Blank et al. · Clinical Cancer Research · 2004 · 55 citations

Medicine, Oncology, Pharmacology +15

Contribution of <i>O</i>⁶‐methylguanine‐DNA methyltransferase to resistance to 1,3‐(2‐chloroethyl)‐1‐nitrosourea in human brain tumor‐derived cell lines

Michael S. Bobola, Mitchel S. Berger, John R. Silber · Molecular Carcinogenesis · 1995 · 51 citations

Medicine, Oncology, Pharmacology +9