The habu genome reveals accelerated evolution of venom protein genes

Hiroki Shibata, Takahito Chijiwa, Naoko Oda‐Ueda, +21

Scientific Reports

Unique structural characteristics and evolution of a cluster of venom phospholipase A2 isozyme genes of Protobothrops flavoviridis snake

Naoki Ikeda, Takahito Chijiwa, Kazumi Matsubara, +4

Gene

BiologyToxinologyNatural SciencesVenomicsUnique Structural Characteristics +3

Flavoxobin, a serine protease from <i>Trimeresurus flavoviridis</i> (habu snake) venom, independently cleaves Arg726‐Ser727 of human C3 and acts as a novel, heterologous C3 convertase

Chieko Yamamoto, Daisuke Tsuru, Naoko Oda‐Ueda, +3

Immunology

Alternative mRNA Splicing in Three Venom Families Underlying a Possible Production of Divergent Venom Proteins of the Habu Snake, Protobothrops flavoviridis

Tomohisa Ogawa, Naoko Oda‐Ueda, Kanako Hisata, +10

Toxins

GeneticsSnake Venom GenesMolecular BiologyPathologyMolecular Genetics +18

Discovery of novel [Arg49]phospholipase A2 isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A2 isozymes in the southwestern islands of Japan and Taiwan

Takahito Chijiwa, Emi Tokunaga, Ryo Ikeda, +6

Toxicon

BiologyToxinologyNatural SciencesVenomicsVenom Phospholipase A2 +3

A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab

Hitomi Nakamura, Naoko Oda‐Ueda, Tadashi Ueda, +1

Biochemical and Biophysical Research Communications

Supramolecular AssemblyProtein AssemblyNatural SciencesMolecular BiologyAdalimumab Fab +5

A [Lys⁴⁹]phospholipase A₂from<i>Protobothrops flavoviridis</i>Venom Induces Caspase-Independent Apoptotic Cell Death Accompanied by Rapid Plasma-Membrane Rupture in Human Leukemia Cells

Tatsuo Murakami, Nobuyuki KAMIKADO, Ryo Fujimoto, +5

Bioscience Biotechnology and Biochemistry

Introduction of a glycosylation site in the constant region decreases the aggregation of adalimumab Fab

Hitomi Nakamura, Naoko Oda‐Ueda, Tadashi Ueda, +1

Biochemical and Biophysical Research Communications

Protein GlycosylationBiochemistryNatural SciencesGlycobiologyMolecular Biology +7

SDS-induced oligomerization of Lys49-phospholipase A2 from snake venom

Takashi Matsui, Shizuka Kamata, Kentaro Ishii, +8

Scientific Reports

Crystal StructureProteinlipid InteractionSignal TransductionToxinologyBiochemistry +13

Case report: Extraocular muscle paresis caused by snakebite.

Tetsuji Takeshita, Kazuhiro Yamada, Masakazu Hanada, +1

PubMed

OphthalmologyOculoplasticsMedicineSurgical PathologyElevation Deficit +8