James V. Heck

Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin:  Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a

Maria A. Bednarek, Scott D. Feighner, Sheng‐Shung Pong et al. · Journal of Medicinal Chemistry · 2000 · 550 citations · Full text

Growth Hormone Secretagogue, Human Growth, Gastrointestinal Peptide Hormone +17

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

Bei Zhang, Gino Salituro, Deborah Szalkowski et al. · Science · 1999 · 453 citations

Insulin Receptor, Insulin Signaling, Cell Surface Receptor +16

Novel 2,3-Dihydrobenzofuran-2-carboxylic Acids:  Highly Potent and Subtype-Selective PPARα Agonists with Potent Hypolipidemic Activity

Guo Q. Shi, James F. Dropinski, Yong Zhang et al. · Journal of Medicinal Chemistry · 2005 · 98 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmacological Study +15

Discovery of a Potent, Highly Selective, and Orally Efficacious Small-Molecule Activator of the Insulin Receptor

Kun Liu, Libo Xu, Deborah Szalkowski et al. · Journal of Medicinal Chemistry · 2000 · 87 citations · Full text

Pharmacotherapy, Insulin Receptor, Classical Quinone-related Phenomena +19

Design and Synthesis of α-Aryloxyphenylacetic Acid Derivatives:  A Novel Class of PPARα/γ Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity

Guo Q. Shi, James F. Dropinski, Brian M. McKeever et al. · Journal of Medicinal Chemistry · 2005 · 77 citations · Full text