Wim-Jan Koot

Solid Phase Synthesis of Bicyclo[2.2.2]octane Derivatives via Tandem Michael Addition Reactions and Subsequent Reductive Amination

Steven V. Ley, Donna M. Mynett, Wim-Jan Koot · Synlett · 1995 · 78 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +16

Synthesis of statine from (S)-malic acid; stereocontrol via radical cyclization

Wim-Jan Koot, Roel van Ginkel, Mirko Kranenburg et al. · Tetrahedron Letters · 1991 · 74 citations

Engineering, Biochemistry, -Malic Acid +6

Michael Additions to (<i>R</i>)-1-Acetyl-5-isopropoxy-3-pyrrolin-2-one and Subsequent <i>N</i>-Acyliminium Ion Generation:  Synthesis of Enantiopure 1-Azabicycles and Preparation of an Intermediate for a Projected Synthesis of Roseophilin

Tim Luker, Wim-Jan Koot, Henk Hiemstra et al. · The Journal of Organic Chemistry · 1998 · 47 citations

Engineering, Michael Additions, Biochemistry +10

Stereoselective synthesis of enantiopure 4,5-disubstituted pyrrolidin-2-ones by consecutive cuprate addition and N-acyliminium coupling

Wim-Jan Koot, Henk Hiemstra, W. N. SPECKAMP · Tetrahedron Letters · 1992 · 33 citations

N-acyliminium Coupling, Organic Chemistry, Consecutive Cuprate Addition +5

Conjugate addition of amines and thiols to (R)-1-acetyl-5-isopropoxy-3-pyrrolin-2-one; Preparation of enantiopure N-acyliminium ion precursors

Wim-Jan Koot, Henk Hiemstra, W. N. SPECKAMP · Tetrahedron Asymmetry · 1993 · 27 citations

Asymmetric Catalysis, Organic Chemistry, Stereoselective Synthesis +5