Daina Zeng

Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design

Xiaofei Liang, Xin Chen, Daina Zeng et al. · Chemistry & Biology · 2010 · 98 citations

Pharmacy, Medicinal Chemistry, Drug Design +10

Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold

Xiaofei Liang, Chul‐Jin Lee, Xin Chen et al. · Bioorganic & Medicinal Chemistry · 2010 · 83 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

Mutants Resistant to LpxC Inhibitors by Rebalancing Cellular Homeostasis*

Daina Zeng, Jinshi Zhao, Hak Suk Chung et al. · Journal of Biological Chemistry · 2013 · 73 citations · Full text

Life Sciences, Cell Biology, Pharmacology +6

Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.

Morgan E. Milton, Bradley M. Minrovic, Danni L. Harris et al. · Frontiers in Molecular Biosciences · 2018 · 27 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile

Rajani Thanissery, Daina Zeng, Raul G. Doyle et al. · Frontiers in Microbiology · 2018 · 24 citations · Full text

Life Sciences, Microbiology, Pharmacology +17