Lou Sing Kan

Triplex formation of oligonucleotides containing 2'-O-methylpseudoisocytidine in substitution for 2'-deoxycytidine

Akira Ono, Paul O. P. Ts’o, Lou Sing Kan · Journal of the American Chemical Society · 1991 · 148 citations

Pharmacy, Molecular Biology, Bioorthogonal Chemistry +11

Detection of a guanine X adenine base pair in a decadeoxyribonucleotide by proton magnetic resonance spectroscopy.

Lou Sing Kan, Srinivasan Chandrasegaran, Stephen M. Pulford et al. · Proceedings of the National Academy of Sciences · 1983 · 132 citations · Full text

Life Sciences, Biochemistry, Chemistry +16

Conformation and interaction of short nucleic acid double-stranded helices. I. Proton magnetic resonance studies on the nonexchangeable protons of ribosyl ApApGpCpUpU

Philip N. Borer, Lou Sing Kan, Paul O. P. Ts’o · Biochemistry · 1975 · 126 citations

Life Sciences, Biochemistry, Molecular Biology +15

DNA triplex formation of oligonucleotide analogs consisting of linker groups and octamer segments that have opposite sugar-phosphate backbone polarities

Akira Ono, C. Chen, Lou Sing Kan · Biochemistry · 1991 · 82 citations

Life Sciences, Biochemistry, Molecular Biology +16

Comparative circular dichroism and fluorescence studies of oligodeoxyribonucleotide and oligodeoxyribonucleoside methylphosphonate pyrimidine strands in duplex and triplex formation

Daniel E. Callahan, Tina L. Trapane, Paul S. Miller et al. · Biochemistry · 1991 · 72 citations

Life Sciences, Biochemistry, Molecular Biology +12