Lucas G. Chase

PDGF, TGF-β, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages

Felicia Ng, Shayne Boucher, Susie Koh et al. · Blood · 2008 · 571 citations

Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

Ruchi Sharma, Vladimir Khristov, Aaron Rising et al. · Science Translational Medicine · 2019 · 356 citations · Full text

Tissue Engineering, Ocular Disease, Clinical-grade Stem +19

A novel serum-free medium for the expansion of human mesenchymal stem cells

Lucas G. Chase, Uma Lakshmipathy, Luis A. Solchaga et al. · Stem Cell Research & Therapy · 2010 · 251 citations · Full text

Toward a Clinical-Grade Expansion of Mesenchymal Stem Cells from Human Sources: A Microcarrier-Based Culture System Under Xeno-Free Conditions

Francisco dos Santos, Pedro Z. Andrade, Manuel M. Abecasis et al. · Tissue Engineering Part C Methods · 2011 · 234 citations

Tissue Engineering, Cell Therapy, Engineering +21

Serum-free, xeno-free culture media maintain the proliferation rate and multipotentiality of adipose stem cells in vitro

Bettina Lindroos, Shayne Boucher, Lucas G. Chase et al. · Cytotherapy · 2009 · 230 citations

Regenerative Medicine, Tissue Engineering, Adipose Stem Cells +9