Kohsuke Mamiya

Genetic Polymorphism of Cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese Population

Miyuki Kimura, Ichiro Ieiri, Kohsuke Mamiya et al. · Therapeutic Drug Monitoring · 1998 · 207 citations

Life Sciences, Genetics, Pharmacology +15

The Effects of Genetic Polymorphisms of CYP2C9 and CYP2C 19 on Phenytoin Metabolism in Japanese Adult Patients with Epilepsy: Studies in Stereoselective Hydroxylation and Population Pharmacokinetics

Kohsuke Mamiya, Ichiro Ieiri, Junta Shimamoto et al. · Epilepsia · 1998 · 174 citations

Medicine, Pharmacokinetics, Pharmacology +15

Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus

Jun Imai, Ichiro Ieiri, Kohsuke Mamiya et al. · Pharmacogenetics · 2000 · 131 citations

Life Sciences, Genetics, Pharmacology +12

Genetic Polymorphism of the CYP2C Subfamily and Excessive Serum Phenytoin Concentration With Central Nervous System Intoxication

Hideaki Ninomiya, Kohsuke Mamiya, S. Matsuo et al. · Therapeutic Drug Monitoring · 2000 · 123 citations

Medicine, Genetics, Pharmacology +15

Catalytic Activity of Three Variants (Ile, Leu, and Thr) at Amino Acid Residue 359 in Human CYP2C9 Gene and Simultaneous Detection Using Single-Strand Conformation Polymorphism Analysis

Ichiro Ieiri, Hitoshi Tainaka, Toshihiro Morita et al. · Therapeutic Drug Monitoring · 2000 · 72 citations

Medicine, Molecular Genetics, Pharmacology +17