Pengfei Yuan

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

Yuexin Zhou, Shiyou Zhu, Changzu Cai et al. · Nature · 2014 · 753 citations

Bioinformatics, Off-target Effect, Engineering +14

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library

Shiyou Zhu, Wei Li, Jingze Liu et al. · Nature Biotechnology · 2016 · 426 citations · Full text

Genetics, Molecular Biology, Gene Editing +6

Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs

Liang Qu, Zongyi Yi, Shiyou Zhu et al. · Nature Biotechnology · 2019 · 267 citations

Rna Processing, Engineering, Natural Sciences +11

Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B

Pengfei Yuan, Hongmin Zhang, Changzu Cai et al. · Cell Research · 2014 · 173 citations · Full text

Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo

Zongyi Yi, Liang Qu, Huixian Tang et al. · Nature Biotechnology · 2022 · 167 citations

Rna Processing, Engineering, In Vivo Gene Therapy +11