Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

Laure Verret, Edward O. Mann, Giao B. Hang, +9

Cell

Alzheimer ModelNeuropsychologyAlzheimer's DiseaseCognitive ScienceBrain Function +9

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model

Pascal E. Sanchez, Lei Zhu, Laure Verret, +8

Proceedings of the National Academy of Sciences

Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

Elsa Suberbielle, Pascal E. Sanchez, Alexxai V. Kravitz, +6

Nature Neuroscience

Neurodegenerative DiseasesMolecular NeuroscienceDna DamageDna Double-strand BreaksPhysiologic Brain Activity +10

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

Moustapha Cissé, Brian Halabisky, Julie A. Harris, +10

Nature

Alzheimer ModelAlzheimer's DiseaseMolecular NeuroscienceDementiaNeurochemical Biomarkers +5

Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network

Julie A. Harris, Nino Devidze, Laure Verret, +10

Neuron

Synaptic PlasticityNeurodegenerative DiseasesSynaptic NeuroscienceSynaptic TransmissionNeurology +7

Life Extension Factor Klotho Enhances Cognition

Dena B. Dubal, Jennifer S. Yokoyama, Lei Zhu, +18

Cell Reports

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory

Anna G. Orr, Edward C. Hsiao, Max Wang, +12

Nature Neuroscience

Molecular PhysiologyMemoryRegulate MemoryNeuroscienceMolecular Neurobiology +1

Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer’s Disease

Magdalena Martínez‐Losa, Tara E. Tracy, Keran Ma, +9

Neuron

Neurodegenerative DiseasesCognitive ScienceAlzheimer's DiseaseNeurobiology Of DiseaseNeurophysiology +9

DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice

Elsa Suberbielle, Biljana Djukic, Mark D. Evans, +9

Nature Communications

Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

Dena B. Dubal, Lei Zhu, Pascal E. Sanchez, +11

Journal of Neuroscience

Synaptic TransmissionImmunologyCell DeathKlotho ExpressionSocial Sciences +24