CJ Eaves

Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta

JD Cashman, AC Eaves, EW Raines et al. · Blood · 1990 · 219 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17

Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis

Christian Sirard, Tsvee Lapidot, Josef Vormoor et al. · Blood · 1996 · 191 citations · Full text

Medicine, Hematology, Oncology +15

Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells.

AC Eaves, JD Cashman, LA Gaboury et al. · Proceedings of the National Academy of Sciences · 1986 · 190 citations · Full text

Life Sciences, Cell Biology, Hematology +13

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells.

CJ Eaves, JD Cashman, Stephen D. Wolpe et al. · Proceedings of the National Academy of Sciences · 1993 · 122 citations

Life Sciences, Cell Biology, Hematology +16

Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia

AL Petzer, CJ Eaves, PM Lansdorp et al. · Blood · 1996 · 116 citations · Full text

Medicine, Hematology, Oncology +16