A.F. Esmail

A tissue-type plasminogen activator mutant with prolonged clearance in vivo. Effect of removal of the growth factor domain.

Molly Browne, J.E. Carey, C.G. Chapman et al. · Journal of Biological Chemistry · 1988 · 88 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Toxicity studies with pure trans-capsaicin delivered to dogs via intravenous administration

Sanjay Chanda, Andrew Mould, A.F. Esmail et al. · Regulatory Toxicology and Pharmacology · 2005 · 29 citations

Pharmacy, Pharmacology, Toxicology +10

Pharmacokinetic Properties of Anisoylated Plasminogen Streptokinase Activator Complex and Other Thrombolytic Agents in Animals and in Humans

Barbara Nunn, A.F. Esmail, Robin Fears et al. · Drugs · 1987 · 27 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

The role of tissue-type plasminogen activator A-chain domains in plasma clearance

Molly Browne, C.G. Chapman, Ian B. Dodd et al. · Fibrinolysis and Proteolysis · 1989 · 17 citations

Life Sciences, Biochemistry, Molecular Biology +13

Deletion of a tripeptide sequence from the growth-factor domain of tissue-type plasminogen activator prolongs in vivo circulation

Molly Browne, C.G. Chapman, Ian B. Dodd et al. · Thrombosis Research · 1990 · 16 citations

Life Sciences, Physiology, Pathophysiology +5