Dominic J. Corkill

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

E. Suzanne Cohen, Ian C. Scott, Jayesh B. Majithiya et al. · Nature Communications · 2015 · 267 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor

John M. Clements, Judy Cossins, Graham Wells et al. · Journal of Neuroimmunology · 1997 · 205 citations

Life Sciences, Immunology, Neurology +17

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

Ian C. Scott, Jayesh B. Majithiya, Caroline Sandén et al. · Scientific Reports · 2018 · 112 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction

Elizabeth England, D. Gareth Rees, Ian C. Scott et al. · Scientific Reports · 2023 · 109 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Development of a mouse model mimicking key aspects of a viral asthma exacerbation

Deborah Clarke, Nicola Davis, Jayesh B. Majithiya et al. · Clinical Science · 2013 · 42 citations

Life Sciences, Immunology, Pharmacology +17