F.A. Fitzpatrick

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

John E. Bleasdale, Nirja Thakur, R S Gremban et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 632 citations

Medicine, Cell Biology, Pharmacology +17

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

F.A. Fitzpatrick, Michael A. Wynalda · Journal of Biological Chemistry · 1983 · 331 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry.

F.A. Fitzpatrick, Michael D. Ennis, Mark E. Baze et al. · Journal of Biological Chemistry · 1986 · 166 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Electrophilic Prostaglandins and Lipid Aldehydes Repress Redox-sensitive Transcription Factors p53 and Hypoxia-inducible Factor by Impairing the Selenoprotein Thioredoxin Reductase

Philip J. Moos, Kornelia Edes, Pamela B. Cassidy et al. · Journal of Biological Chemistry · 2003 · 164 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Redox Signaling, Alkylation (Carbonylation) of Conserved Cysteines Inactivates Class I Histone Deacetylases 1, 2, and 3 and Antagonizes Their Transcriptional Repressor Function

Kelly Doyle, F.A. Fitzpatrick · Journal of Biological Chemistry · 2010 · 139 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16