pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16<i>^INK4a</i> tumor suppressor gene

Yojiro Kotake, Ru Cao, Patrick Viatour, +3

Genes & Development

Long Noncoding RNA ANRIL Regulates Proliferation of Non-small Cell Lung Cancer and Cervical Cancer Cells.

Madoka Naemura, Chihiro Murasaki, Yasutoshi Inoue, +2

PubMed

Human Immunodeficiency Virus Type 1 Vpr-Binding Protein VprBP, a WD40 Protein Associated with the DDB1-CUL4 E3 Ubiquitin Ligase, Is Essential for DNA Replication and Embryonic Development

Chad M. McCall, Paula L. Miliani de Marval, Paul D. Chastain, +5

Molecular and Cellular Biology

Viral ReplicationImmunologyMolecular BiologyHiv-1 VprCell Cycle +16

Role of Serine 10 Phosphorylation in p27 Stabilization Revealed by Analysis of p27 Knock-in Mice Harboring a Serine 10 Mutation

Yojiro Kotake, Keiko Nakayama, N. Ishida, +1

Journal of Biological Chemistry

P27 Knock-in MiceMolecular BiologyP27 StabilizationCell CycleTranscriptional Regulation +16

DDB1-CUL4 and MLL1 Mediate Oncogene-Induced p16<i>INK4a</i> Activation

Yojiro Kotake, Yaxue Zeng, Yue Xiong

Cancer Research

Molecular RegulationMolecular BiologyP16 LocusEpigeneticsTumor Biology +14

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

Tiffany Hung, Yulei Wang, Michael F. Lin, +19

Nature Genetics

Transcriptional RegulationGeneticsCoordinated TranscriptionGene TranscriptionGene Expression +5

<scp>YB</scp>‐1 promotes transcription of <i>cyclin D1</i> in human non‐small‐cell lung cancers

Masanori Harada, Yojiro Kotake, Tatsuya Ohhata, +7

Genes to Cells

High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers

Mai Shimada, Kyoko Kitagawa, Yoh Dobashi, +9

Cancer Science

Transcriptional Regulation of the p16 Tumor Suppressor Gene.

Yojiro Kotake, Madoka Naemura, Chihiro Murasaki, +2

PubMed

Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein.

Yojiro Kotake, Kyoko Kitagawa, Tatsuya Ohhata, +5

PubMed