Grace Chan

Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein

Xiaoyan Chu, Kelly Bleasby, Jocelyn Yabut et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 175 citations

Pitavastatin is a more sensitive and selective organic anion‐transporting polypeptide<scp>1B</scp>clinical probe than rosuvastatin

Thomayant Prueksaritanont, Xiaoyan Chu, Raymond Evers et al. · British Journal of Clinical Pharmacology · 2014 · 162 citations · Full text

Discovery of 1-Amino-5<i>H</i>-pyrido[4,3-<i>b</i>]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders

Jongwon Lim, Brandon M. Taoka, Ryan D. Otte et al. · Journal of Medicinal Chemistry · 2011 · 73 citations · Full text

Janus Kinase 2, Jak-stat Pathway Mediates, Pharmacotherapy +19

Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design

Xiaojing Wang, Steven Magnuson, Rich Pastor et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 67 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Property-based Drug Design +10

Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans

Xiaoyan Chu, Shian‐Jiun Shih, Rachel Shaw et al. · Drug Metabolism and Disposition · 2015 · 59 citations