James I. Last

Cancer Risks and Mortality in Heterozygous ATM Mutation Carriers

Deborah J. Thompson, Silvia Duedal, Jennifer Kirner et al. · JNCI Journal of the National Cancer Institute · 2005 · 544 citations

Life Sciences, Genetics, Oncology +17

Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: A genotype-phenotype study

Mijke M.M. Verhagen, James I. Last, Frans B.L. Hogervorst et al. · Human Mutation · 2011 · 172 citations

Life Sciences, Genetics, Molecular Genetics +17

Ataxia telangiectasia mutated–deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

Tatjana Stanković, Grant S. Stewart, Chris Fegan et al. · Blood · 2002 · 133 citations · Full text

Life Sciences, Genetics, Oncology +13

Residual Ataxia Telangiectasia Mutated Protein Function in Cells from Ataxia Telangiectasia Patients, with 5762ins137 and 7271T→G Mutations, Showing a Less Severe Phenotype

Grant S. Stewart, James I. Last, Tatjana Stanković et al. · Journal of Biological Chemistry · 2001 · 105 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Hypomorphic PCNA mutation underlies a human DNA repair disorder

Emma L. Baple, Helen Chambers, Harold E. Cross et al. · Journal of Clinical Investigation · 2014 · 98 citations · Full text

Life Sciences, Genetics, Molecular Biology +17