Donna Amrán

Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells

Adrián M. Ramos, Carlos Fernández, Donna Amrán et al. · Blood · 2005 · 94 citations · Full text

Medicine, Oncology, Pharmacology +17

Genistein selectively potentiates arsenic trioxide‐induced apoptosis in human leukemia cells <i>via</i> reactive oxygen species generation and activation of reactive oxygen species‐inducible protein kinases (p38‐MAPK, AMPK)

Yolanda Sánchez, Donna Amrán, Carlos Fernández et al. · International Journal of Cancer · 2008 · 73 citations

Medicine, Oncology, Pharmacology +13

Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4)

Yolanda Sánchez, Donna Amrán, Elena de Blas et al. · Biochemical Pharmacology · 2008 · 56 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +5

12-O-Tetradecanoylphorbol-13-acetate May Both Potentiate and Decrease the Generation of Apoptosis by the Antileukemic Agent Arsenic Trioxide in Human Promonocytic Cells

Carlos Fernández, Adrián M. Ramos, Patricia Sancho et al. · Journal of Biological Chemistry · 2004 · 47 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Pharmacologic inhibitors of extracellular signal‐regulated kinase (ERKs) and c‐Jun NH₂‐terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia Cells to arsenic trioxide‐induced apoptosis

Adrián M. Ramos, Carlos Fernández, Donna Amrán et al. · Journal of Cellular Physiology · 2006 · 44 citations

Life Sciences, Oncology, Pharmacology +17