Lisa P. Walker

A Novel Mode of Action for a Microbial-Derived Immunotoxin: The Cytolethal Distending Toxin Subunit B Exhibits Phosphatidylinositol 3,4,5-Triphosphate Phosphatase Activity

Bruce J. Shenker, Mensur Dlakić, Lisa P. Walker et al. · The Journal of Immunology · 2007 · 113 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activates the NLRP3 Inflammasome in Human Macrophages, Leading to the Release of Proinflammatory Cytokines

Bruce J. Shenker, David M. Ojcius, Lisa P. Walker et al. · Infection and Immunity · 2015 · 65 citations · Full text

Life Sciences, Immunology, Microbiology +17

Blockade of the PI-3K signalling pathway by the<i>A</i><i>ggregatibacter actinomycetemcomitans</i>cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cytokines

Bruce J. Shenker, Lisa P. Walker, Ali Zekavat et al. · Cellular Microbiology · 2014 · 56 citations · Full text

Life Sciences, Immunology, Microbiology +17

The toxicity of the<i>Aggregatibacter actinomycetemcomitans</i>cytolethal distending toxin correlates with its phosphatidylinositol-3,4,5-triphosphate phosphatase activity

Bruce J. Shenker, Kathleen Boesze‐Battaglia, Monika Scuron et al. · Cellular Microbiology · 2015 · 33 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Internalization

Kathleen Boesze‐Battaglia, Lisa P. Walker, Ali Zekavat et al. · Infection and Immunity · 2015 · 22 citations · Full text

Life Sciences, Immunology, Microbiology +17