Donald L. Zignego

Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids

Donald L. Zignego, Jonathan K. Hilmer, Ronald K. June · Journal of Biomechanics · 2015 · 57 citations · Full text

Mechanobiology, Musculoskeletal Research, Engineering +8

Candidate mediators of chondrocyte mechanotransduction via targeted and untargeted metabolomic measurements

Aaron A. Jutila, Donald L. Zignego, Bradley K. Hwang et al. · Archives of Biochemistry and Biophysics · 2014 · 40 citations · Full text

Tissue Engineering, Mechanobiology, Untargeted Metabolomic Measurements +12

Encapsulation of Chondrocytes in High-Stiffness Agarose Microenvironments for In Vitro Modeling of Osteoarthritis Mechanotransduction

Aaron A. Jutila, Donald L. Zignego, William Schell et al. · Annals of Biomedical Engineering · 2014 · 38 citations

Tissue Engineering, Mechanobiology, Regenerative Medicine +13

The mechanical microenvironment of high concentration agarose for applying deformation to primary chondrocytes

Donald L. Zignego, Aaron A. Jutila, Martin K. Gelbke et al. · Journal of Biomechanics · 2013 · 30 citations · Full text

Regenerative Medicine, Tissue Engineering, Mechanobiology +8

Inhibition of early response genes prevents changes in global joint metabolomic profiles in mouse post-traumatic osteoarthritis

Dominik R. Haudenschild, Alyssa K. Carlson, Donald L. Zignego et al. · Osteoarthritis and Cartilage · 2018 · 30 citations

Inflammation, Rheumatoid Disorder, Anti-inflammatory +9